Newsletter: Ateneo scientists research potential anti-ulcer vaccine

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Since ancient times, it was thought that painful stomach ulcers were caused by eating spicy foods or having an unhealthy diet. But since then, researchers have found that Helicobacter pylori—a common bacterium found in over 60% of the world’s population—was the real culprit behind most stomach ulcers and a high risk for stomach cancer. 

Amnesia-causing diatoms found in Luzon shellfish farms

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The densely-populated island of Luzon is home to over half of the Philippines’ population, many of whom consume shellfish on a regular basis. An international team of scientists has just confirmed the presence there of two species of Pseudo-nitzschia diatoms capable of producing a dangerous neurotoxin that can cause severe sickness and memory loss. 

Light microscope and transmission electron microscope photographs of Pseudo-nitzschia pungens var. Pungens (top two photos) and Pseudo-nitzschia brasiliana (bottom two photos) found in Luzon shellfish farms. Both species produce domoic acid, a dangerous neurotoxin. CREDIT: Botavara et al.

Poetically described as “algae that live in glass houses,” diatoms are microscopic aquatic organisms that cover themselves in protective milk-colored silica shells. While most diatom species are harmless, half of the 58 known species from the genus Pseudo-nitzschia are notorious for producing domoic acid (DA). A person who has eaten DA-infected shellfish may experience vomiting, nausea, diarrhea, and abdominal cramps. In some cases, DA has even caused the permanent loss of short-term memory in a condition known as “amnesic shellfish poisoning” (ASP).